What happened in the hospital, stays in the hospital
We get a flashback of the last time Shane saw Rick in the hospital. It is utter chaos. The military is shooting everybody in site and zombies are roaming the halls. He pulls a gurney to Rick's room and tries to take Rick out. A soldier peeks in the room and Shane hides. He unplugs Rick from his machine and listens to Rick's heart. It appears that he doesn't hear anything (the machine showed Rick was still alive and his heart beating) and he leaves pulling the gurney in front of the door so the zombies won't get in.
We just want a chance
For a minute there it seemed like the doors to the CDC wouldn't open and they were going to have to fight to the death to get back to their cars. Jenner allows them in with the condition that they all submit to blood tests. They agree and the door closes behind them.
Test Subject 19
Test subject 19 is the sample Jenner was working on to find a cure to the disease. He shows the group a video of the infected test subject in an MRI. We see the patient die and then part of the brain come back to life a couple of hours after death. Jenner shot the patient in the head when it became a zombie. That patient was Jenner's wife. We learn that revival times vary from person to person. They don't know what the disease is or how to stop it. The French were the last hold outs that Jenner heard from. So we now know the epidemic is global and not just the US.
Oh, Shane
Shane attacks Lori in the rec room. He tells her he loves her and that they are a couple. She pushes him off and scratches him. He was drunk, but I believe him when he says that he loves her. I think he has loved her for a long time. He has seen Lori and Carl as family for years. Then Rick gets shot, the epidemic begins, he thinks (or wishes) Rick is dead and he finally gets to be with Lori. Once Rick comes back Lori completely cuts him out due to her own guilt. Lori is also mad at Shane for telling her that Rick was dead. This only adds to her guilt. Shane tells Lori that he didn't hear a heartbeat but he says it was because of the gunshots. The question is whether or not that is true. It could have been wishful thinking on his part that Rick's heart wasn't beating. Either way, Shane has lost everything and he is starting to unravel.
It's the final countdown
There is a clock counting down in the big room at the CDC. It turns out that the CDC has been running on generators for a while now and there is no more fuel left for them. The fail safe kicks in. This means the CDC will self-destruct in order to prevent the spread of disease. The CDC stores all kinds of deadly and contagious diseases. The last thing the world needs is another epidemic on top of the current zombie inducing epidemic. Jenner is ready to go down with the ship. He refuses to let the group out. Daryl tries to open the door by hitting it repeatedly with an axe. Eventually, Rick convinces Jenner to let them go. He lets them out of the big room. Jenner stays as well as Jackie and Andrea. Dale decides that if Andrea is going to stay then he is going to stay. Once they leave the big room they run into the problem that the outer doors won't open because their is no more power left to open them. They end up blowing up a window with the grenade that Rick grabbed while trapped in the tank (which Carol kept). As they turn to leave Jenner whispers something into Rick's ear. (The answer to what he whispered is revealed in the season 2 finale.) At the last minute Andrea and Dale run out of the building. Andrea did not want to be responsible for Dale's death.
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